Research Vision

At the Translational Organ Microsystems (TOM) Group, we develop biomimetic and predictive human organ models to bridge the gap between preclinical discovery and clinical translation, with a particular focus on the lung.

To answer this question, we investigate four interconnected research directions:

• Engineering Human Organ Microsystems
  Development of biomimetic organ-on-chip platforms through advanced biofabrication, microengineering, and modular tissue technologies.
• Decoding Disease Mechanisms
  Understanding how mechanical cues, extracellular matrix remodeling, and mechanotransduction regulate pulmonary health and disease.
• Capturing Immune Complexity
  Integration of immune cells and host–pathogen interactions into physiologically relevant tissue models.
• Advancing Translational Medicine
  Supporting drug discovery, repurposing, and PK/PD studies using predictive human-relevant systems.