Publications

Selected Publications

Airway-on-Tube Graphical Abstract
Advanced Materials (2026)

Hydrogel-Based Airway-on-Tube with Perfusable Endothelial Lumen and Outward Epithelialization

Doryab A., Murphy J.F., Bartolf-Kopp M., Hsin J., Chernaik A., McCaughan F., Huang Y., Jungst T., Groll J.

A hydrogel-based airway-on-tube platform featuring a perfusable endothelial lumen and outward epithelialization, enabling more physiologically relevant modeling of airway biology and vascular interactions.

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Thorax publication
Thorax (2026)

Breathing immunity into in vitro lung models

Doryab A., Heydarian M., Bryant C., Conway Morris A.

This state of the art review examines the development of immune-competent in vitro lung models and their potential to improve disease modelling and therapeutic discovery. It highlights key challenges in integrating immune cells while discussing emerging solutions through organ-on-chip technologies, tunable extracellular matrices, bioprinting, and engineered microvascular networks.

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Lung Fibrosis Model
Advanced Materials (2022)

Real-Time Measurement of Cell Mechanics as a Clinically Relevant Readout of an In Vitro Lung Fibrosis Model Established on a Bioinspired Basement Membrane

Doryab A., Taskin M., Stahlhut P., Groll J., Schmid O.

Demonstrates how cell mechanical properties can serve as a clinically relevant readout for fibrosis progression using a biomimetic lung tissue model.

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Biomimetic In Vitro Lung Models
Advanced Materials (2023)

Biomimetic In Vitro Lung Models: Current Challenges and Future Perspective

Doryab A., Groll J.

A Perspective discussing the current challenges and potential strategies toward not only bioinspired but truly biomimetic lung models.

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Lung-on-Chip Fabrication
Advanced Functional Materials (2024)

Fabrication Strategies for Bioinspired and Functional Lung-on-Chips

Doryab A., Braig J., Jungst T., Ryma M., Groll J.

Overview of fabrication approaches used to develop advanced lung-on-chip platforms with improved physiological relevance and functionality.

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Neonatal Lung Injury
American Journal of Physiology – Lung Cellular and Molecular Physiology (2026)

A Biomimetic Miniaturized In Vitro Model to Target Early Markers of Neonatal Pulmonary Vascular Injury

Heydarian M., Doryab A., Henao J., Schubert B., Schmid O., Hilgendorff A.

Miniaturized biomimetic model developed to investigate early pulmonary vascular injury mechanisms relevant to neonatal lung disease.

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